NAD+ SCIENCE
Discover The Science Behind NAD+
NAD+ powers your body’s energy metabolism and plays a vital role in DNA repair, cellular function, and a healthy immune response.
The critical role of NAD+ in cellular health
NAD+ is a vital coenzyme present in every cell of the body, including those in the heart, brain, muscles, and lungs. It transforms nutrients into usable energy and supports essential metabolic processes by regulating how our cells function.By transferring electrons between molecules, NAD+ powers the production of cellular energy and plays a key role in maintaining the body’s circadian rhythm, the internal clock that governs our sleep–wake cycle.
NAD+ supports metabolism in two essential ways. First, it enables the conversion of nutrients into usable cellular energy. Second, it acts as a coenzyme, working alongside key proteins that regulate critical cellular processes.Together, these functions help maintain overall health, support healthy ageing, and promote resilience against a range of age-related conditions.
How NAD+ can help you
NAD+ plays a key role in supporting metabolic pathways, DNA repair, cellular ageing, and immune cell function, both directly and indirectly.These processes are essential for maintaining strong physical and mental health, enhancing the body’s resilience to illness, and promoting healthy ageing.
NAD+ levels naturally decline with age, and this reduction is associated with cognitive decline, metabolic dysfunction, increased frailty, and other age-related changes. Research suggests that supporting or restoring NAD+ levels may help slow, and in some cases potentially counteract, aspects of biological ageing.As a result, NAD+ metabolism has become a key focus in the search for strategies that promote healthy ageing and support a longer healthspan, the years of life spent in good health.
Human Performance
Our personalised NAD+ protocols are tailored to meet your unique needs, ensuring that you perform at your best, whether you’re facing a career-defining presentation, a challenging workout, or any endeavour that demands peak performance.
Enhanced Energy Production
NAD+ plays a vital role in supporting mitochondrial function, the energy-producing powerhouse of the cell, helping to optimise energy production and promote greater endurance.
Improved Mental Clarity and Focus
Optimising NAD+ levels may support cognitive function, helping to enhance mental focus, improve clarity, and promote overall cognitive performance.
Enhanced Athletic Performance
Optimising NAD+ levels may support athletic performance by promoting healthy muscle function, improving endurance, and helping to reduce feelings of fatigue.
Increased Resilience and Endurance
By supporting cellular resilience, NAD+ helps your body better withstand the demands of intense physical and mental exertion, while also promoting faster, more efficient recovery.
Longevity
At NADclinic, we specialise in addressing the key biological factors that influence ageing, vitality, and long-term wellbeing through personalised NAD+ protocols. Discover the power of NAD+ and take meaningful steps toward a longer, healthier, and more vibrant life.
Enhanced Cellular Function
NAD+ supplementation supports healthy mitochondrial function, helping to optimise cellular energy production and promote overall vitality and wellbeing.
DNA Repair and Maintenance
NAD+ plays an essential role in supporting DNA repair processes, helping to maintain genomic stability and limit the accumulation of age-related cellular damage.
Improved Metabolic Health
Optimising NAD+ levels may help support healthy metabolic function, including the regulation of glucose and lipid metabolism, key processes that contribute to long-term health and longevity.
Increased Resilience to Stress
NAD+ supplementation may help support healthy cellular stress responses, enhancing the body’s resilience to environmental and oxidative stressors and contributing to long-term wellbeing.
Sexual Health
Our personalised therapies are designed to help individuals regain confidence and control in their sexual wellness, supporting fulfilment and satisfaction at every stage of life.
Optimised Hormonal Balance
NAD+ supports healthy cellular processes that influence hormone regulation, helping to promote balance and stability within the body’s endocrine system.
Hormonal Support for Menopause & Andropause
NAD+ therapy may help support hormonal balance and overall wellbeing during menopause and andropause, contributing to improved energy, mood stability, and sexual wellness as the body adapts to age-related hormonal changes.
Enhanced Libido & Sexual Vitality
By supporting healthy cellular function and overall vitality, NAD+ may help enhance libido, boost desire, and promote deeper intimacy and connection.
Boosting Fertility
By supporting healthy cellular function, NAD+ may contribute to overall reproductive wellness for both men and women, helping to create conditions that support optimal reproductive health.
Sleep & Circadian Rhythm
Your circadian rhythm is the body’s internal biological clock, operating on a roughly 24-hour cycle. It regulates essential functions including the sleep–wake cycle, hormone release (such as melatonin and cortisol), body temperature, and key processes involved in digestion and metabolism.
Sleep Wake Cycles
NAD+ plays a vital role in regulating your body’s natural sleep–wake rhythm, your internal biological clock that keeps you energised by day and restores you at night. By supporting the cellular processes that influence melatonin release, cortisol balance, and metabolic regulation, NAD+ helps synchronise your circadian rhythm for deeper, more restorative sleep.
Hormone Release (Melotonin, Cortisol)
NAD+ plays an essential role in regulating key hormones that shape your sleep, energy, and daily performance. By supporting the cellular pathways that influence melatonin and cortisol production, NAD+ helps maintain a healthy hormonal rhythm throughout the day.Melatonin, the hormone responsible for preparing your body for deep, restorative sleep, relies on balanced NAD+ levels for optimal release. Cortisol, your natural “wake-up” and stress-response hormone, also depends on NAD+ to stay in sync, ensuring you feel energised in the morning and calm as the day winds down.By harmonising these hormonal patterns, NAD+ promotes better sleep quality, steadier energy levels, and a more resilient stress response, helping you feel grounded and balanced from morning to night.
Body Temperature
Your body’s ability to maintain a stable temperature is essential for overall health, energy, and performance, and NAD+ plays a quiet yet powerful role in keeping this internal climate in balance.As a key regulator of cellular energy production, NAD+ helps fuel the metabolic processes that generate heat, allowing your body to adapt effortlessly to changes in your environment. Whether you’re cooling down for restful sleep or warming up for daily activity, NAD+ supports the smooth functioning of the systems that maintain thermal stability.By optimising cellular efficiency, NAD+ contributes to a more consistent and responsive temperature-regulation cycle, helping you feel comfortable, balanced, and at your best throughout the day and night.
Digestion & Metobolism
Healthy digestion and efficient metabolism are the foundation of energy, vitality, and long-term wellness and NAD+ plays a central role in both.As a key coenzyme in cellular energy production, NAD+ helps convert the nutrients you eat into usable fuel, supporting everything from digestive efficiency to metabolic balance. By optimising how your cells process carbohydrates, fats, and proteins, NAD+ promotes smoother digestion and a more stable, responsive metabolic system.Enhanced NAD+ levels can improve nutrient absorption, support healthy gut function, and help regulate metabolic pathways that influence weight, energy levels, and overall vitality. The result is a more balanced digestive system and a metabolism that works with you, not against you, keeping you energised, nourished, and performing at your best.
Hair & Skin
Grounded in scientific research, NAD+ plays an important role in supporting healthy cellular function, which can positively influence the condition of your skin and hair. By promoting cellular repair and energy production from within, NAD+ helps maintain a vibrant, healthy, and more youthful-looking appearance.
Improved Skin Health
NAD+ supports healthy cellular regeneration and plays a role in collagen-producing pathways, helping to maintain firmer, smoother, and more youthful-looking skin.
Enhanced Oxygen Flow
Optimal oxygen flow is essential for energy, mental clarity, and peak physical performance and NAD+ plays a vital role in making it all possible.By supporting mitochondrial efficiency, NAD+ helps your cells use oxygen more effectively, improving the way your body converts oxygen into clean, sustainable energy. This enhanced cellular respiration means your tissues, muscles, and organs receive the oxygen they need to function at their highest level.
Cellular Regeneration
NAD+ plays an important role in supporting cellular repair and regeneration, helping to promote healthy skin cell renewal and overall skin vitality.
Combat Hair Loss
NAD+ supplementation supports healthy cellular function within the hair follicles, helping to promote stronger, healthier-looking hair. By enhancing cellular repair and energy production, NAD+ may contribute to improved hair vitality, thickness, and overall scalp health.
Metabolic Syndrome & Weight Loss
Our protocols are expertly designed to address the key drivers of metabolic imbalance, providing personalised interventions tailored to your individual metabolic needs for more effective, sustainable results.
Diabetes Management
Optimising NAD+ levels may help support healthy glucose metabolism and insulin sensitivity, contributing to more balanced blood sugar regulation and overall metabolic wellbeing.
Obesity
By supporting healthy mitochondrial function and promoting efficient fat metabolism, NAD+ supplementation may contribute to improved energy balance and support healthy weight management as part of a holistic wellness approach.
Metabolic Syndrome
NAD+ supplementation may help support key aspects of metabolic health by promoting healthy cellular energy production, balanced lipid metabolism, and overall metabolic efficiency. This holistic support can contribute to improved vitality and long-term metabolic wellbeing.
Liver Disease
NAD+ plays an essential role in supporting healthy liver function and natural detoxification processes. By promoting optimal cellular energy and repair within liver cells, NAD+ contributes to overall liver health and resilience, helping the body manage metabolic stress more effectively.
Degradation Vs Colour Change
It’s a common misconception that any yellowish colour in NAD⁺ means the product has gone bad, but that’s simply not true. In fact, a gentle yellow tint is completely normal for pure, high-quality NAD⁺. Clear NAD+ is unnatural and an indication of synthetic stabilizers and non-pure food grade NAD+NAD⁺ is naturally sensitive to its environment, and variations in colour can occur without affecting its potency or effectiveness. Only significant, prolonged exposure to heat, light, or moisture leads to real degradation.So, if your NAD⁺ has a slight yellow hue, rest assured, it’s a natural characteristic of pure NAD⁺ and not a sign of reduced quality.
Browse the Research
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FAQs
Find quick answers to the most common questions about our NAD+ products.
A CE-certified, single-use auto-injector delivering 50mg–125mg of ultra-pure NAD+ via a high-precision spring mechanism.
- Only NAD+ made in an MHRA, NHS, GMP-approved facility
- Includes anti-tamper & anti-counterfeit features
- 99.9% purity, triple filtration, and full safety certification
Yes — our pen and solution are medically certified. Always follow instructions and consult your clinician before beginning.
Using naturally fermented, enzymatically purified raw materials under sterile pharmaceutical conditions with third-party testing.
Yes. Our NAD+ is one of the only legally registered formulations worldwide, and the NADSQ X Pen is CE-certified.
Each pen includes:
- Serialised tracking
- Batch-specific Certificates of Analysis
- External safety validation
- Tamper-evident packaging