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Read the science behind NAD+ and its health benefits

From increased energy to clearer thinking, NAD+ can support your health and wellbeing across a number of areas. But don't just take our word for it - read the latest scientific research into NAD+ and it benefits on this page.

NAD+ Research

Click the link to read research in full detail.

Anti-Ageing

NAD+ in Aging: Molecular Mechanisms and Translational Implications

Promotes Healthy Mitochondria

NAD+ boosting reduces age-associated amyloidosis and restores mitochondrial homeostasis in muscle

Optimises Brain Performance

NAD+ in brain aging and neurodegenerative disorders

Reduce Neurodegenerative Disorders

Targeting NAD+ degradation: The therapeutic potential of flavonoids for Alzheimer's disease and cognitive frailty

Reduce Long Covid

Treatment of SARS-CoV-2-induced pneumonia with NAD+ and NMN in two mouse models

Improves Physical Performance

Healthy aging and muscle function are positively associated with NAD+ abundance in humans

Repairs & Maintains Healthy DNA

NAD+ in DNA repair and mitochondrial maintenance

Fights Signs of Fatigue

The Role of Kynurenine Pathway and NAD+ Metabolism in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Maximises Cellular Health

NAD+ metabolism and its roles in cellular processes during ageing

Fortifies Your Immune System

NAD+ metabolism, stemness, the immune response, and cancer

Alcohol Detox & Protection of the Liver

Hepatic NAD+ deficiency as a therapeutic target for non-alcoholic fatty liver disease in ageing

Weight Loss & Accelerated Metabolism

Weight Loss Is Associated With Increased NAD+/SIRT1 Expression But Reduced PARP Activity in White Adipose Tissue

Insulin Resistance & Diabetes

Impaired nicotinamide adenine dinucleotide (NAD+) metabolism in diabetes and diabetic tissues: Implications for nicotinamide‐related compound treatment

Rescues Female Fertility

NAD+ repletion rescues female fertility during reproductive aging

Relief of Depression

Nicotinamide, a vitamin B3 ameliorates depressive behaviors independent of SIRT1 activity in mice