Optima Max Spermidine

Take 1 capsule per day with water. 

Spermidine is typically used daily and consistently, as its benefits are associated with long-term cellular processes rather than immediate effects.

⚠️ Do not exceed the recommended daily intake.

✔ Individuals looking to support cellular renewal and maintenance
✔ Those interested in healthy ageing and longevity-focused nutrition
✔ People seeking to support autophagy as part of a wellness routine
✔ Individuals following science-led, preventative health approaches
✔ Those complementing NAD+, fasting, or metabolic optimisation protocols

Spermidine and NAD+ support different but complementary cellular pathways:

• Spermidine supports autophagy and cellular renewal
  
• NAD+ plays a central role in cellular energy metabolism and repair
  
  Together, they are often used within longevity-focused routines to support both cellular energy and cellular clean-up processes, forming a balanced, mechanism-based approach to healthy ageing.

For advanced longevity support, combine Spermidine with Optima Max CaAKG and Pure Collagen to support renewal, structure and visible vitality.

Take 1 capsule per day with water. 

Spermidine is typically used daily and consistently, as its benefits are associated with long-term cellular processes rather than immediate effects.

⚠️ Do not exceed the recommended daily intake.

✔ Individuals looking to support cellular renewal and maintenance
✔ Those interested in healthy ageing and longevity-focused nutrition
✔ People seeking to support autophagy as part of a wellness routine
✔ Individuals following science-led, preventative health approaches
✔ Those complementing NAD+, fasting, or metabolic optimisation protocols

Spermidine and NAD+ support different but complementary cellular pathways:

• Spermidine supports autophagy and cellular renewal
  
• NAD+ plays a central role in cellular energy metabolism and repair
  
  Together, they are often used within longevity-focused routines to support both cellular energy and cellular clean-up processes, forming a balanced, mechanism-based approach to healthy ageing.

For advanced longevity support, combine Spermidine with Optima Max CaAKG and Pure Collagen to support renewal, structure and visible vitality.

Autophagy is the cellular self-cleaning process by which the body identifies, breaks down, and recycles damaged proteins and organelles. Declining autophagy with age contributes to cellular damage accumulation. Spermidine supports autophagy activation, helping maintain cellular health.

NAD+ supports cellular energy metabolism and DNA repair, while spermidine supports cellular autophagy and renewal. Together they address two distinct but complementary hallmarks of ageing.

3mg per day is consistent with doses used in spermidine research and mirrors the intake in studies showing associations with reduced mortality. It is considered a well-tolerated and meaningful supplementation amount.

Yes. Epidemiological studies in human cohorts have associated higher dietary spermidine intake with reduced cardiovascular and all-cause mortality. Multiple preclinical studies across species show direct mechanistic evidence of longevity extension via autophagy.

As with all food supplements, certain individuals should exercise caution. This includes people who are pregnant or breastfeeding, those with pre-existing medical conditions, individuals currently taking prescription medication (including blood thinners, diabetes medication, immunosuppressants, or thyroid medication), and those under the age of 18. Supplements are not intended to diagnose, treat, cure, or prevent any disease. We strongly recommend that every client consults a qualified healthcare professional before starting any new supplement, particularly if they have an existing health condition or are taking medication. When in doubt, escalate to the NADclinic clinical team.