Optima Max - SirtPro Activator

Take one capsule per day with water before a meal

Berberine is typically used daily and consistently, often alongside meals, as its benefits are associated with ongoing metabolic support rather than immediate effects.

⚠️ Do not exceed the recommended daily intake.

✔ Individuals looking to support healthy glucose and insulin balance
✔ Those focused on metabolic health and weight management strategies
✔ People seeking to support cardiovascular and lipid metabolism
✔ Individuals aiming to maintain energy efficiency and metabolic resilience
✔ Those following science-led, preventative wellness approaches
✔ Individuals complementing NAD+, longevity, or metabolic optimisation protocols

Berberine and NAD+ support complementary aspects of cellular metabolism:

• Berberine supports metabolic signalling pathways involved in glucose regulation and energy balance
  
• NAD+ plays a central role in cellular energy production and redox reactions
  

Together, they are often used in longevity-focused routines to support both metabolic regulation and cellular energy, helping create a balanced, mechanism-based approach to metabolic health and healthy ageing.

• Supports healthy blood sugar levels
• Enhances insulin sensitivity
• Promotes fat metabolism and weight balance
• Supports cardiovascular and gut health

For a complete metabolic stack, combine Berberine with Optima Max CaAKG, GlyNac and the NAD+ Smart Pen. This combination supports energy regulation, antioxidant protection and cellular longevity.

Take one capsule per day with water before a meal

Berberine is typically used daily and consistently, often alongside meals, as its benefits are associated with ongoing metabolic support rather than immediate effects.

⚠️ Do not exceed the recommended daily intake.

✔ Individuals looking to support healthy glucose and insulin balance
✔ Those focused on metabolic health and weight management strategies
✔ People seeking to support cardiovascular and lipid metabolism
✔ Individuals aiming to maintain energy efficiency and metabolic resilience
✔ Those following science-led, preventative wellness approaches
✔ Individuals complementing NAD+, longevity, or metabolic optimisation protocols

Berberine and NAD+ support complementary aspects of cellular metabolism:

• Berberine supports metabolic signalling pathways involved in glucose regulation and energy balance
  
• NAD+ plays a central role in cellular energy production and redox reactions
  

Together, they are often used in longevity-focused routines to support both metabolic regulation and cellular energy, helping create a balanced, mechanism-based approach to metabolic health and healthy ageing.

• Supports healthy blood sugar levels
• Enhances insulin sensitivity
• Promotes fat metabolism and weight balance
• Supports cardiovascular and gut health

For a complete metabolic stack, combine Berberine with Optima Max CaAKG, GlyNac and the NAD+ Smart Pen. This combination supports energy regulation, antioxidant protection and cellular longevity.

Standard berberine powder has poor bioavailability and much of it is not absorbed. Berbersome® encapsulates berberine in a phospholipid layer, dramatically improving absorption (10 times versus standard) and ensuring more of the active molecule reaches target tissues.

AMPK (AMP-activated protein kinase) is a key cellular energy sensor and longevity pathway. It is activated by calorie restriction and exercise, and regulates glucose uptake, fat burning, and mitochondrial function. Berberine is one of the most potent natural AMPK activators known.

Clients on blood glucose-lowering medications must consult their physician before adding berberine, as it has glucose-lowering effects that may require medication adjustment. Always escalate to the clinical team.

15 to 30 minutes before a carbohydrate-rich meal for optimal glucose metabolism support.

As with all food supplements, certain individuals should exercise caution. This includes people who are pregnant or breastfeeding, those with pre-existing medical conditions, individuals currently taking prescription medication (including blood thinners, diabetes medication, immunosuppressants, or thyroid medication), and those under the age of 18. Supplements are not intended to diagnose, treat, cure, or prevent any disease. We strongly recommend that every client consults a qualified healthcare professional before starting any new supplement, particularly if they have an existing health condition or are taking medication. When in doubt, escalate to the NADclinic clinical team.