NAD+ Benefits

Anti-Ageing	NAD+ in Aging: Molecular Mechanisms and Translational Implications
Promotes Healthy Mitochondria	NAD+ boosting reduces age-associated amyloidosis and restores mitochondrial homeostasis in muscle
Optimises Brain Performance	NAD+ in brain aging and neurodegenerative disorders
Reduce Neurodegenerative Disorders	Targeting NAD+ degradation: The therapeutic potential of flavonoids for Alzheimer's disease and cognitive frailty
Reduce Long Covid	Treatment of SARS-CoV-2-induced pneumonia with NAD+ and NMN in two mouse models
Improves Physical Performance	Healthy aging and muscle function are positively associated with NAD+ abundance in humans
Repairs & Maintains Healthy DNA	NAD+ in DNA repair and mitochondrial maintenance
Fights Signs of Fatigue	The Role of Kynurenine Pathway and NAD+ Metabolism in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Maximises Cellular Health	NAD+ metabolism and its roles in cellular processes during ageing
Fortifies Your Immune System	NAD+ metabolism, stemness, the immune response, and cancer
Alcohol Detox & Protection of the Liver	Hepatic NAD+ deficiency as a therapeutic target for non-alcoholic fatty liver disease in ageing
Weight Loss & Accelerated Metabolism	Weight Loss Is Associated With Increased NAD+/SIRT1 Expression But Reduced PARP Activity in White Adipose Tissue
Insulin Resistance & Diabetes	Impaired nicotinamide adenine dinucleotide (NAD+) metabolism in diabetes and diabetic tissues: Implications for nicotinamide‐related compound treatment
Rescues Female Fertility	NAD+ repletion rescues female fertility during reproductive aging
Relief of Depression	Nicotinamide, a vitamin B3 ameliorates depressive behaviors independent of SIRT1 activity in mice

Anti-Ageing

NAD+ in Aging: Molecular Mechanisms and Translational Implications

Promotes Healthy Mitochondria

NAD+ boosting reduces age-associated amyloidosis and restores mitochondrial homeostasis in muscle

Optimises Brain Performance

NAD+ in brain aging and neurodegenerative disorders

Reduce Neurodegenerative Disorders

Targeting NAD+ degradation: The therapeutic potential of flavonoids for Alzheimer's disease and cognitive frailty

Reduce Long Covid

Treatment of SARS-CoV-2-induced pneumonia with NAD+ and NMN in two mouse models

Improves Physical Performance

Healthy aging and muscle function are positively associated with NAD+ abundance in humans

Repairs & Maintains Healthy DNA

NAD+ in DNA repair and mitochondrial maintenance

Fights Signs of Fatigue

The Role of Kynurenine Pathway and NAD+ Metabolism in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Maximises Cellular Health

NAD+ metabolism and its roles in cellular processes during ageing

Fortifies Your Immune System

NAD+ metabolism, stemness, the immune response, and cancer

Alcohol Detox & Protection of the Liver

Hepatic NAD+ deficiency as a therapeutic target for non-alcoholic fatty liver disease in ageing

Weight Loss & Accelerated Metabolism

Weight Loss Is Associated With Increased NAD+/SIRT1 Expression But Reduced PARP Activity in White Adipose Tissue

Insulin Resistance & Diabetes

Impaired nicotinamide adenine dinucleotide (NAD+) metabolism in diabetes and diabetic tissues: Implications for nicotinamide‐related compound treatment

Rescues Female Fertility

NAD+ repletion rescues female fertility during reproductive aging

Relief of Depression

Nicotinamide, a vitamin B3 ameliorates depressive behaviors independent of SIRT1 activity in mice

Licenses & Regulation: All NADdirect products and supplements are manufactured in GMP facilities adhering to the strictest quality control and safety regulations.

We are a London-based NAD+ supplements online store. For more information, please email support@naddirect.com or call +44 (0)207 935 1155.

NADdirect is part of the NADclinic group of companies. Company Number: 12000410

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NAD+ Research

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NAD+ Research

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